5α-Reductase
Converts testosterone to dihydrotestosterone (DHT). Target of finasteride.
Gene Name
SRD5A1/SRD5A2
Enzyme Class
reductase
Molecular Weight
28,600 Da
Protein Structure Databases
Reduces the C4-C5 double bond of testosterone to produce the more potent androgen DHT.
Precursor
Testosterone
Test
This enzyme plays a crucial role in steroid hormone biosynthesis. Genetic variations or inhibition can significantly impact hormone levels and related physiological processes.