@fluxStyles

CYP11B1

Cytochrome P450 Family 11 Subfamily B Member 1

Compendium
Enzymes
CYP11B1

CYP11B1

Cytochrome P450 Family 11 Subfamily B Member 1

11β-hydroxylase in zona fasciculata. Final step in cortisol synthesis.

Gene Name

CYP11B1

Enzyme Class

hydroxylase

Molecular Weight

58,000 Da

Protein Structure Databases

UniProt: P15538

Function

Catalyzes the hydroxylation of 11-deoxycortisol to cortisol.

Clinical Significance

This enzyme plays a crucial role in steroid hormone biosynthesis. Genetic variations or inhibition can significantly impact hormone levels and related physiological processes.