@fluxStyles

CYP11B2

Cytochrome P450 Family 11 Subfamily B Member 2

Compendium
Enzymes
CYP11B2

CYP11B2

Cytochrome P450 Family 11 Subfamily B Member 2

Aldosterone synthase in zona glomerulosa. Final steps in aldosterone synthesis.

Gene Name

CYP11B2

Enzyme Class

hydroxylase

Molecular Weight

58,000 Da

Protein Structure Databases

UniProt: P19099

Function

Catalyzes the final three steps of aldosterone biosynthesis from corticosterone.

Clinical Significance

This enzyme plays a crucial role in steroid hormone biosynthesis. Genetic variations or inhibition can significantly impact hormone levels and related physiological processes.