Compounds Involved
Type
dangerous
Severity
danger
Evidence Level
clinical
Dose Dependent
Yes
Effect Description
Both are 19-nor compounds. Stacking increases risk of prolactin-related side effects and cardiovascular strain.
Mechanism
Dual progestogenic activity can lead to severe prolactin elevation, gynecomastia, and sexual dysfunction. Also compounds cardiovascular stress.
Timing Considerations
Avoid stacking these compounds
Monitoring Requirements
If stacking despite warnings, monitor prolactin, blood pressure, and lipids weekly